This PhD project is investigating the links between radon gas, UV radiation and skin cancer.
The South West of England has some of the country’s highest levels of radon, a naturally occurring gas, with concentrations exceeding more than 6 times the national average in some locations.
Radon is a known carcinogen and has been shown to be the second leading cause of lung cancer behind smoking. Recent work suggests a link between radon and skin cancer, though such a link has not yet been proven.
This research aims to investigate the cellular and molecular effects of radon within different types of cultured human skin cells. It will explore how radon might add to the cellular damage created by exposure to UV radiation, commonly experienced by spending time in the sun.
It builds upon existing research which uses novel experimentation techniques, and may help to inform changes in national guidelines for recommended radon exposure.